General Pharmacology

Subtopics

• Pharmacokinetics: absorption, Vd, clearance, half-life Resource →
• Zero-order vs first-order kinetics (phenytoin, ethanol, aspirin) Resource →
• Pharmacodynamics: agonists/antagonists, Emax & potency curves Resource →
• CYP450 induction & inhibition / major drug–drug interactions Resource →
• Autonomic pharmacology: cholinergic & adrenergic agonists/antagonists Resource →
• Toxicology & antidotes (acetaminophen→NAC, opioids→naloxone, benzos→flumazenil, iron→deferoxamine, methanol/ethylene glycol→fomepizole) Resource →
• Adverse drug reactions & hypersensitivity mechanisms Resource →
• FDA clinical trial phases (0–4) & pharmacovigilance Resource →

Prerequisites

• General Pharmacology

Leads To

• General Pharmacology
• General Pharmacology

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